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We employed an adeno-associated virus vector (AAV2/8) to deliver and express either human wild-type hepsin (hHPN WT

At the time of admission he weighed 740 pounds (335.6 kg, BMI 95.1), which had precluded the patient from being a surgical candidate due to concern that the operating-room table would not support his weight, in addition to his severe medical problems listed above

Three types of deiodinase enzymes, all selenium-dependent selenoproteins, control thyroid hormone activation and deactivation

Several linear (Manier et al., 2020) and non-linear strategies (QC-Robust Smoothing Splines (QC-RSC) (Kirwan et al., 2013), QC-Support vector regression correction (QC-SVRC)) (Moreno-Torres et al., 2021) have been proposed for the modeling of within-batch effects