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Cellular and porcine models were used to evaluate the safety of microneedle-assisted copper peptide delivery

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Keywords: vitamin B-12, folic acid, folate, holotranscobalamin, homocysteine, methylmalonic acid, pernicious anemia Statement of Significance : There is significant circumstantial evidence that excess folic acid consumption exacerbates vitamin B-12 insufficiency, but a biochemical/physiological mechanism has not yet been identified