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Even the vital biologic systems can create an energy deficit that needs to be restored

The discovery that melatonin enhances the survival and function of insulin-producing -cells [136] adds more support to the idea that melatonin plays a role in regulating insulin signaling

Two trials in acutely hospitalized patients have shown that short-term (around 7 days) vitamin C supplementation increased concentrations of ascorbic acid in plasma and leukocytes and led to 34-35% improvements in mood state, as measured by POMS (142, 143)