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Ribociclib plus letrozole versus chemotherapy for postmenopausal women with hormone receptor-positive, HER2negative, luminal B breast cancer (CORALLEEN): an open-label, multicentre, randomised, phase 2 trial
& LeDoux, J
Regul Toxicol Pharmacol 32(1):5667 Park BK, Boobis A, Clarke S, Goldring CE, Jones D, Kenna JG, Lambert C, Laverty HG, Naisbitt DJ, Nelson S, Nicoll-Griffith DA, Obach RS, Routledge P, Smith DA, Tweedie DJ, Vermeulen N, Williams DP, Wilson ID, Baillie TA (2011) Managing the challenge of chemically reactive metabolites in drug development
With other formulations you need to take up to four grams daily, which can lead to loose stools and upset stomach
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