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Funding This work was supported by the Natural Science Foundation of Henan Province (222300420089), the National Natural Science Foundation of China (32371170, 31971065), the Scientific Research and Innovation Team of the First Affiliated Hospital of Zhengzhou University (QNCXTD2023006), and the Medical Science and Technology Research Project of Henan Province (LHGJ20230165)

The benefits of NAC administration in heterogeneous causes of acute liver failure demonstrate that GSH augmentation can improve clinical outcomes in diverse conditions that lead to hepatic oxidative stress and not just acute acetaminophen toxicity

2022 to 2023: Tirzepatide was approved for type 2 diabetes (Mounjaro) in May 2022 and for weight management (Zepbound) in November 2023