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doi: 10.3390/ijms16047210 [DOI] [PMC free article] [PubMed] [Google Scholar] 76.Schairer DO, Chouake JS, Kutner AJ, Makdisi J, Nosanchuk JD, Friedman AJ

Methods: In this randomized, active comparator-controlled, open-label study, 145 subjects with NAFLD (18-70 y, BMI 25-50 kg/m 2 , stable body weight, without T2DM or with T2DM with an A1C 8.5% controlled by diet stable dose of metformin) and LFC 10% (measured by MRI PDFF) at screening were randomized 1:1 to EFI 10 mg QW or SEMA 1.0 mg QW (titrated to target doses over 8 weeks) for 24 weeks