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[1] [2] While no dose adjustment is required for renal impairment, patients with kidney issues should be monitored for potential dehydration and kidney injury, especially if experiencing severe gastrointestinal adverse reactions

Quick Answer: Tirzepatide modulates rather than eliminates hunger, and persistent appetite can result from insufficient dosage, early treatment phase, individual response variability, lifestyle factors, or normal physiological needs

And it all started because I was just curious to find out how we can help people solve their own problems instead of trying to figure out medications to solve the problems