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Once released, these cholesterol precursors interact with LDLR of T cells, driving their polarization towards a Th17 phenotype through activation of the transcription factor RORt, which has immunosuppressive functions ( 4.1.4 Prostate cancer Prostate cancer, which accounts for 7.3% of all cancers diagnosed worldwide, is the second most common cancer in men

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Li S, Luo X, Zhang S, Su Y, Deng M, Zhu Y, et al