In addition, three important antioxidant enzymes, GST, SOD, and ascorbate peroxidase (APX), displayed significantly higher activities in transgenic lines after inoculation with F
Compared with GPX1-3, GPX4 is also involved in the reduction of complex membrane-associated phospholipid hydroperoxides such as phosphatidylcholine hydroperoxide and cholesterol hydroperoxide, in addition to reacting with soluble, low molecular weight hydroperoxides such as t-butyl hydroperoxide and cumene hydroperoxide [68]
Spider venomics: implications for drug discovery
Composed of glutamic acid, cysteine, and glycine, glutathione plays a critical role in maintaining redox balance, supporting detoxification processes, and protecting cells from oxidative stress