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Megadoses of up to 2,000 mcg are considered safe in treating a B12 deficiency, but its best to avoid excessive amounts of any vitamins, especially when not needed
Prevalence and clinical significance of RBM3 immunostaining in non-small cell lung cancers
Prato A, Randazzo M, Messina MA, Puglisi G, Aleo LR, Ciantia F, Cirnigliaro L, Rizzo R, Barone R
Specifically, CSCs dependent on OXPHOS have been observed to maintain robust ATP production even when glycolytic intermediates or glucose are scarce, allowing them to withstand radiotherapy or chemotherapy that targets rapidly proliferating, highly glycolytic cells
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