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Finally, a discussion emerged regarding a specific population that may significantly benefit from combined therapy: individuals with obesity and T2D and high or very high cardiovascular risk or obesity

Fasting triggers a cascade of metabolic benefits, including: Increased insulin sensitivity Enhanced GLP-1 secretion Reduced appetite and cravings Improved fat burning Studies show that even short fastslike a 12- to 16-hour fasting windowcan elevate GLP-1 and improve metabolic flexibility

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