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Furthermore, both genetic depletion and chemical inhibition of zinc accumulation effectively safeguard SC- cells from identity loss and enhance their efficacy in diabetic animals

The density of the ECD linker (E127 ECD -P137 ECD ), ECL1 (T207 ECL1 -Q213 ECL1 /L218 ECL1 ) and ICL3 (N338 ICL3 -D344 ICL3 ) regions of both exendin 4 and oxyntomodulin complexes were discontinuous and these sequences were omitted from the final models