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S.SadeghsoltaniF.BazmaniA.et al (2025)

Gastrointestinal adverse events Compared with placebo, nausea was more frequent with all tirzepatide doses, especially 15 mg (OR 5.60 [95% CI 3.12, 10.06], I 2 0%) (Table 2)

Probiotic Bacteria Are Not Likely to Cause Bloating Though this might seem counterintuitive, its highly unlikely that the healthy bacteria in a probiotic formula are to blame for bloating or other digestive issues 1 2

For additional perspective on how peptides compare with other treatment modalities, our guide on peptides versus TRT provides a framework for thinking about peptide therapy in the broader context of regenerative medicine