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Potential Side Effects High doses can produce adverse reactions such as insomnia, anxiety, or fatigue if escalated too quickly

Genomics studies for indigenous high-altitude populations like Tibetans, Andeans, Ethiopians, and Sherpas have identified 169 genes under positive natural selection

We observed a marked decrease of gastric epithelial cell proliferation rates, protection against parietal cell death and a 90% reduction of gastritis, accompanied by normalized expression levels for all (pro-inflammatory) cytokines, confirming the suppression of the host immune response elicited by Helicobacter infection

In triple-negative breast cancer (TNBC), mutant p53 induces nonclassical apoptosis via aberrant interaction with MDM2, independent of wild-type p53 [49]