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Physical enhancement methods including iontophoresis, microneedling, and ultrasound also significantly increase GHK-Cu delivery, with microneedling pre-treatment increasing peptide penetration by approximately 10-fold compared to intact skin application, effects similar to those achieved with other topical peptide formulations optimized for transdermal delivery

Low dose naltrexone resulted in significant clinical improvement in 75%, and complete remission in 25% of patients

In fact it is in some ways surprising that it is normal to shed as many as 100 hairs per day