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Potassium supplements taken concurrently with b12 injections may theoretically reduce b12 effectiveness, but this interaction rarely causes clinical problems

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In a glycemic control trial evaluating a dose comparable to the 9 mg dose and the 25 mg semaglutide tablet doses in patients with T2D, 1.3% and 1.9% of patients in the 9 mg and 25 mg semaglutide group, respectively, reported moderate-severe non-proliferative diabetic retinopathy events, and 0% and 0.4% reported proliferative retinopathy events, respectively

After 28 days, bacterial growth risk increases even with bacteriostatic water, and peptide degradation becomes significant