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Cai X, Cai J, Fang L, Xu S, Zhu H, Wu S, Chen Y, Fang S

The direct relationship between tryptophan levels and depressive symptoms and fatigue has been demonstrated by Trp depletion experiments, as reviewed elsewhere [76], and is also of interest in the context of long-term COVID, as recent studies have shown a significant decrease in plasma Trp levels in PASC patients [48], and alterations in kynurenine pathway metabolites have been associated with cognitive impairment in long COVID patients [27], as well as with anxiety and depressive symptoms in COVID-19 survivors 6 months post-infection [66]

These tablets contain 3 additives , microcrystalline cellulose, tricalcium phosphate and magnesium stearate, and are considered acceptable with low toxicity

That starts with the basics of who these drugs are designed for