The thyroid gland has several functions, including: Regulating metabolism, growth, and development Modulating body temperature Regulating mood (along with the endocrine and nervous systems) In a healthy individual, the pituitary gland (in the brain) releases thyroid stimulating hormone, or TSH, to signal the thyroid to produce adequate amounts of thyroid hormones
If your hs-CRP is elevated, it means your body is stuck in a state of chronic immune activation, which is a major, and often overlooked, driver of brain fog and accelerated ageing
The upregulation of these enzymes directly leads to excessive breakdown of core ECM components in cartilage, such as type II collagen and aggrecan
Figure 1 5 Future directions and conclusion Although studies directly investigating the effects of urolithin A on sleep are lacking, there is mechanistic plausibility supporting this potential relationship, representing a novel direction in polyphenol-derived microbial metabolite research