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found that TMAO promoted the release of pro-inflammatory cytokines such as IL-1 and TNF- to stimulate the cardiac autonomic nervous system (CANS) and worsen ischemia-induced VA (127)

Initial research tested doses as low as 250mcg and as high as 1mg daily

Potential Side Effects and Long-Term Risks Common side effects include nausea, vomiting, digestive issues, and fatigue

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