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But the reduction is often disproportionate, hitting protein intake harder than other macronutrients because protein-rich foods tend to be the most satiating and the hardest to consume when appetite is suppressed

Switching from Semaglutide GLP-1 to tirzepatide can offer enhanced weight loss results, improved medication adherence, and better management of comorbidities

This is not a pharmacokinetic effect but rather a physiological one

GLP-1 agonists have the highest regain rate after discontinuation because the appetite suppression effect disappears, leading many people to regain 60-70% of lost weight within a year